1 Choline chloride based eutectic solvent: a highly efficient reaction media for the synthesis of 3,4-dihydropyrimidin-2(1H)-thiones https://jourcc.com/index.php/jourcc/article/view/jcc434 10.52547/jcc.4.3.4 1 A mild and green protocol was developed to the 3,4-dihydropyrimidin-2(1H)-thione derivatives preparation in deep eutectic solvent without the use of a catalyst or any other additive. The procedure offers a number of benefits, including clean reaction profile, avoiding the use of typical toxic catalysts, an easy workup procedure, short reaction times, and low prices. 153 157 Fatemeh Malamiri Ahvaz Branch, Islamic Azad University (IAU) Iran info@jourcc.com Rashid Badri Ahvaz Branch, Islamic Azad University (IAU) Iran info@jourcc.com Samad Khaksar Ayatollah Amoli Branch, Islamic Azad University (IAU) Iran Ayatollah Amoli Branch, Islamic Azad University (IAU) The University of Georgia Georgia Iran s.khaksar@ug.edu.ge Peyman Salahshour The University of Georgia Georgia info@jourcc.com Deep Eutectic Solvent Green solvent Dihydropyrimidine Multicomponent Biginelli condensation Article4.pdf [1] P. Liu, J.-W. Hao, L.-P. Mo, Z.-H. Zhang, Recent advances in the application of deep eutectic solvents as sustainable media as well as catalysts in organic reactions, RSC Advances 5(60) (2015) 48675-48704.##[2] C. Ruß, B. 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