1 Application of carbon allotropes composites for targeted cancer therapy drugs: A review https://jourcc.com/index.php/jourcc/article/view/jcc327 10.52547/jcc.3.2.7 20.1001.1.26765837.2021.3.7.7.2 1 In recent years, various drug carrier nanomaterials have been investigated to improve drug delivery systems in cancer treatment. However, an ongoing requirement exists for more beneficial therapeutic materials, yielding rapid clearance, high capacity for reducing systemic toxicity via specific-tumor targeting, and superior drug solubility. Given that, carbon allotropes, including Active Carbon (AC), carbon nanotubes (CNTs), graphene and graphene oxides (GOs), nanodiamonds (NDs), fullerenes, carbon nanohorns, soporous carbons, and carbon dots, have been studied owing to their high thermal conductivity, rigid structure, flexibility for modification and functionalization, adequate surface-to-volume ratio, and high biocompatibility. This review aims to overview recent advances in applying different carbon allotrope composites in drug delivery-based cancer therapy systems. 140 151 Firooze Niazvand Abadan Faculty of Medical Sciences Iran info@jourcc.com Pushkaraj Rajendra Wagh Western University of Health Sciences United States info@jourcc.com Elham Khazraei Tarbiat Modares University Iran info@jourcc.com Mahsa Borzouyan Dastjerdi National Institute of Genetic Engineering and Biotechnology Iran Mahsaborzouyan@gmail.com Chanakya Patil Texas Tech University Health Sciences Center USA info@jourcc.com Ishtiyaq Ahmad Najar UT of Jammu and Kashmir India info@jourcc.com Carbon allotropes Drug Delivery Cancer therapy Nanocomposites Nanomaterials Article7.pdf [1] W. Chen, K. Sun, R. Zheng, H. Zeng, S. Zhang, C. Xia, Z. Yang, H. Li, X. Zou, J. He, Cancer incidence and mortality in China, 2014, Chinese journal of cancer research 30(1) (2018) 1.## [2] B. Hosnedlova, M. Kepin-ska, C. Fernandez, Q. Peng, B. Ruttkay‐Nedecky, H. 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