1 Sr-doped bioactive glasses for biological applications https://jourcc.com/index.php/jourcc/article/view/jcc227 10.29252/jcc.2.2.7 20.1001.1.26765837.2020.2.3.7.7 1 In this work, sol–gel derived bioactive glasses (BGs) system of 60% SiO2-(36-x) CaO-4P2O5-x SrO (where x = 2, 4, 6 and 8 mol%) were obtained. The bioactivity and proliferation of G292 cells was investigated for Sr-containing BGs. X-ray diffraction analysis (XRD), Scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR) were utilized to study the obtained phases, hydroxyapatite (HA) morphology, and its functional groups, respectively. The XRD and FTIR tests showed that the rate of hydroxyapatite formation on sample 2S was higher than that of other samples. Also 3-(4,5 dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay performed after one day revealed that the sample containing 6 mol% of Sr (6S) showed higher viability. However, the sample with 8 mol% Sr (8S) showed a decrease in bioactivity in osteoblast G292 cells proliferation. According to the results, 6S BG specimen with 6 mol% SrO exhibited appropriate bioactivity and cell proliferation. This finding showed that the obtained BGs could be potentially used for drug delivery systems as well as dental and orthopedic applications. 105 109 Zahra Goudarzi Amirkabir University of Technology Iran info@jourcc.com Amir Ijadi Amirkabir University of Technology Iran info@jourcc.com Ameneh Bakhtiari Shahid Chamran University Iran bakhtiariaa@yahoo.com Sara Eskandarinezhad Yazd University Iran info@jourcc.com Negar Azizabadi Science and Research Branch, Islamic Azad University (IAU) Iran info@jourcc.com Mohammadreza Asgari Jazi Isfahan (Khorasgan) Branch, Islamic Azad University (IAU) Iran info@jourcc.com Bioactive glass Implant Strontium Article7.pdf [1] L.L. 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