1 TZNT alloy for surgical implant applications: A systematic review https://jourcc.com/index.php/jourcc/article/view/jcc221 10.29252/jcc.2.2.1 20.1001.1.26765837.2020.2.3.1.1 1 Nowadays, Ti–Nb–Ta–Zr ‎ (TZNT) alloy ‎ have attracted attention as new β titanium alloy material for surgical implant applications due to its biocompatibility, great corrosion behavior, low ‎cytotoxicity, and enhanced wear resistance, biological and mechanical properties. There is a great need to improve the implant properties which can be achieved through a combined solution of β titanium alloy (TNZT) with low elastic modulus in the physiological environment of the body. Moreover, it protects the surgical implant from inflammation, infection, adverse soft tissue reaction to particulate debris and implant fracture. Therefore this review aimed to improve the quality of the surgical implant applications to enhance the working life and prevent failure ‎by adding four matrices containing niobium, zirconium, tantalum, and silicon. Hence, TZNT alloy can be developed to be a promising candidate for biomedical applications especially in surgical implant applications. 62 68 Kiana Alimohammadi Khajeh Nasir Toosi University of Technology (KNTU) Iran info@jourcc.com Leila Bazli Iran University of Science and Technology Iran leilabazli64@gmail.com Sara Eskandarinezhad Yazd University Iran info@jourcc.com Ali Mohammadi Tehran Medical Sciences, Islamic Azad University (IAU) Iran info@jourcc.com Niloufar Sheysi Tehran Medical Sciences, Islamic Azad University (IAU) Iran info@jourcc.com TZNT alloy Surgical implant Biomedical Article1.pdf [1] E. Sharifi Sedeh, S. Mirdamadi, F. Sharifianjazi, M. 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