1 Wearable biosensors incorporating nanocomposites: advancements, applications, and future directions 1 Wearable sensors have emerged as transformative tools, enabling real-time monitoring of human health and activities. Within this field, miniaturized and flexible devices have attracted significant attention due to their compact size, ease of use, and non-invasive operation. These sensors function by detecting biological activities and converting bio-signals such as electrophysiological, mechanical, and biochemical information into quantifiable data. Such data can be obtained through various sensing approaches, including the detection of electrolytes, ions, and gases. In many cases, wearable sensors are fabricated by integrating the sensing element into a polymer matrix, with nanomaterials playing a particularly important role in enhancing performance. Health monitoring remains the primary application area for these devices. Emerging technologies, including AI-assisted sensing and cloud-based data processing, are expected to drive future advancements, while also introducing challenges related to data privacy. Looking ahead, key areas of development for nanomaterial-based wearable sensors include non-contact monitoring, textile-integrated devices, and improvements in security and regulatory frameworks. 1 10 Nadia Banitorfi Hoveizavi Department of Textile Engineering, Isfahan University of Technology, Isfahan, 84156-83111 Iran n.banitorfi@tx.iut.ac.ir Mina Laghaei Univ. Lille, ENSAIT, ULR 2461 – GEMTEX – Génie des Matériaux Textiles, F-59000 Lille France mina-sadat.laghaei-khoulenjani@ensait.fr Shima Tavakoli Translational Chemical Biology Group, Division of Macromolecular Chemistry, Department of Chemistry-Ångstrom Laboratory, Uppsala University, Uppsala, SE75121 Sweden Shima.tavakoli@kemi.uu.se Behrouz Javanmardi Department of Textile Engineering, Amirkabir University of Technology, Tehran Iran jawanmardy@gmail.com Nanocomposites Wearable sensors Textile-based wearable sensors Health monitoring [1] J. Heikenfeld, A. Jajack, J. Rogers, P. Gutruf, L. Tian, T. Pan, R. Li, M. Khine, J. Kim, J. Wang, Wearable sensors: modalities, challenges, and prospects, Lab on a Chip 18(2) (2018) 217-248.##[2] Z. Karimzadeh, M. Mahmoudpour, E. Rahimpour, A. 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